Resume:

Yan Wu , Professor. She received her Ph.D. degree from NanKai University in 2003, and was a Postdoctoral fellow at FuDan University during 2003-2005. She joined National Center for Nanoscience and Technology, China (NCNST) in 2005, and is a Professor at NCNST now. Her research interests include: synthesis and characterization of multifunctional polymer drug carriers; and construction and application of drug-loaded nanoparticles in vitro and in vivo. Until now more than 40 scientific papers have been published in the international and domestic journals.

Direction:

1.Synthesis and characterization of multifunctional polymer drug carriers.

2. Construction and application of drug-loaded nanoparticles in vitro and in vivo.

Peer-reviewed publications:

1. Xiongwei Deng, Minjun, Jiakun Zhang, Kelei Hu, Zhaoxia Yin, Zhixiang Zhou, Xiangqian Xiao, Yishu Yang, Wang Sheng *,Yan Wu*, Yi Zeng. Hyaluronic acid-chitosan nanoparticles for co-delivery of MiR-34a and doxorubicin in therapy against triple negative breast cancer. Biomaterials, 2014, 35,4333-4344.

2. Shishuai Su, Hai Wang, Xiaoguang Liu, Yan Wu*, Guangjun Nie*. iRGD-coupled responsive fluorescent nanogel for targeted drug delivery. Biomaterials, 2013, 34,3523-3533.

3. Minjun Cao,Xiongwei Deng,Shishuai Su,Fang Zhang,Xiangqian Xiao,Qin Hu,Yongwei Fu,Burton B. Yang, Yan Wu*, Wang Sheng*, Yi Zeng. Protamine sulfate–nanodiamond hybrid nanoparticles as a vector for MiR-203 restoration in esophageal carcinoma cells. Nanoscale, 2013, 5, 12120 -12125.

4. Siyuan Han, Yuexian Liu, Xin Nie, Qing Xu, Fang Jiao, Wei Li, Yuliang Zhao, Yan Wu *, Chunying Chen*. Ef?cient Delivery of Antitumor Drug to the Nuclei of Tumor Cells by Amphiphilic Biodegradable Poly( L-Aspartic Acid-co-Lactic Acid)/DPPE Co-Polymer Nanoparticles, Small, 2012, 8,1596-1606.

5. Qing Xu, Yuexian Liu, Shishuai Su, Wei Li, Chunying Chen*, Yan Wu*. Anti-tumor activity of paclitaxel through dual- targeting carrier of cyclic RGD and transferrin conjugated hyperbranched copolymer nanoparticles, Biomaterials, 2012, 33, 1627-1639.

6. Yan Wu, Fang Jiao, Siyuan Han, Tengfei Fan, Ying Liu, Wei Li, Liming Hu, Yuliang Zhao, Chunying Chen*. Construction of amphiphilic copolymer nanoparticles based on hyperbranched Poly (Amine-Ester) and 1,2-Dipalmitoyl-Sn-Glycero-3-Phosphoethanolamine as drug carriers for cancer therapy. Nanomedicine: Nanotechnology, Biology, and Medicine,2011,7,945-954.

7.Qinghua Miao, Dongxue Xu, Zhi Wang, Li Xu, Tiewei Wang, Yan Wu*, David B. Lovejoy, Danuta S. Kalinowski, Des R. Richardson*, Guangjun Nie*, Yuliang Zhao. Amphiphilic hyper-branched co-polymer nanoparticles for the controlled delivery of anti-tumor agents. Biomaterials, 2010,31:7364-7375.

8. Jingxia Gu, Fan Xia, Yan Wu*, Xiaozhong Qu, Zhenzhong Yang, Lei Jiang. Programmable delivery of hydrophilic drugs using dually responsive hydrogel cages. Journal of controlled release, 2007, 117: 396-402.

E-mail: wuy@nanoctr.cn