Name: Chen Wang                         

Education: Ph.D.

Academic title: Professor

Postal Code: 100190                     

Mailing Address: No.11，Beiyitiao Zhongguancun Beijing,china      

E-mail: wangch@nanoctr.cn

Resume:

C. Wang received his B.S. degree from University of Science and Technology of China in 1986. After obtaining his PhD from University of Virginia in 1992, he joined Arizona State University as a postdoctoral associate. In 1994, he became a professor of Central China Normal University. He was a faculty of the Institute of Chemistry, Chinese Academy of Sciences from 1995 to 2004, and is currently a professor and director of National Center for Nanoscience and Technology of China.

Research in the Wang group focuses on many aspects of surface physical chemistry and nano-bio interface, including the principle of scanning tunneling microscopy and its applications, nanoscale physical and chemical phenomena at intersurface, and molecular self-assembly, and single molecule physics and chemistry, etc. In recent years, his group has been engaged in the molecular mechanisms of peptide assembly and its modulation, and dedicated to disease diagnosis and treatment techniques based on peptide nanostructures. He has been involved in several major projects as PI, such as Major Program of NSFC, Key Project of Chinese Academy of Sciences (CAS), and National Basic Research Program of China (“973” Program, Ministry of Science and Technology, MOST). In recognition of his research he has been several important awards. He has delivered many invited lectures in international academic conference. He has published more than 200 papers in international peer-reviewed journals including Chem. Soc. Rev., Proc. Natl. Acad. Sci., J. Am. Chem. Soc., Angew. Chem. Int. Ed., Nano Lett. etc. He published 4 books in Chinese or English.

Direction:

1. Scanning probe microscopy and its applications

2. Single molecule chemistry and physics

3. Peptide self-assembly and its modulation

4. Design, construction and characterization of molecular nanostructures

Achievements:

1. Outstanding Young Scientist of Chinese Academy of Sciences (1997)

2. Young Chemist Award of Chinese Chemical Society (1998)

3. Outstanding Young Scientist of Chinese Academy of Sciences (1999)

4. Young Scholar Award of “Qiushi Technology and Science Foundation” (Hong Kong 1999)

5. The 2nd Prize for Technological Advancement of Chinese People's Liberation Army (1999)

6. The 1st Prize for Technological Advancement of the Ministry of Education (2003, the 2nd awardee)

7. Achievement Award for Science and Technology of Chinese Vacuum Society (2005)

Article:

1. Lei Liu, Lin Niu, Meng Xu, Qiusen Han, Hongyang Duan, Mingdong Dong, Flemming Besenbacher, Chen Wang*, Yanlian Yang*, “Molecular tethering effect of C-terminus of amyloid peptide Aβ42”, ACS Nano, 2014, 8(9), 9503-9510.

2. Shelley A. Claridge, Jeffrey J. Schwartz, Miles A. Silverman, John C. Thomas, Yanlian Yang,* Chen Wang,* and Paul S. Weiss*, “Differentiating Amino Acid Residues and Side Chain Orientations in Peptides Using Scanning Tunneling Microscopy”, J. Am. Chem. Soc., 2013,135(49), 18528–18535.

3. Xiaobo Mao, Yuanyuan Guo, Yin Luo, Lin Niu, Lei Liu, Xiaojing Ma, Huibin Wang, Yanlian Yang*, Guanghong Wei*, Chen Wang*, “Sequence Effects on Peptide Assembly Characteristics Observed by Using Scanning Tunneling Microscopy”, J. Am. Chem. Soc., 2013, 135 (6), 2181–2187.

4. Xiaobo Mao, Chenxuan Wang, Xingkui Wu, Lei Liu, Lan Zhang, Lin Niu, Yanlian Yang*, Chen Wang*,“Beta structure motifs of islet amyloid polypeptides identified through surface-mediated assemblies”, Proc. Natl. Acad. Sci. USA, 2011, 108, 9605-19610.

5. Lei Liu, Lan Zhang, Lin Niu, Meng Xu, Xiaobo Mao, Yanlian Yang*, Chen Wang*, “Observation of Reduced Cytotoxicity of Aggregated Amyloidogenic Peptides with Chaperone-like Molecules”, ACS Nano, 2011, 5, 6001-6007.

6. Yong-Tao Shen, Ke Deng, Xue-Mei Zhang,Wei Feng, Qing-Dao Zeng*, Chen Wang*, Jian Ru Gong, “Switchable Ternary Nanoporous Supramolecular Network on Photo-Regulation”, Nano Lett., 2011, 11, 3245-3250.

7. Yanlian Yang, Chen Wang*, “Hierarchical construction of self-assembled low-dimensional molecular architectures observed by using scanning tunneling microscopy”, Chem. Soc. Rev., 2009, 38, 2576-2589.

8. Yong-Tao Shen, Li Guan, Xiao-Yang Zhu, Qing-Dao Zeng*, Chen Wang*, “Submolecular Observation of Photosensitive Macrocycles and Their Isomerization Effects on Host-Guest Network”, J. Am. Chem. Soc., 2009, 131, 6174–6180.

9. Lei Liu, Lan Zhang, Xiaobo Mao, Lin Niu, Yanlian Yang*, Chen Wang*, “Chaperon-mediated Single Molecular Approach Towards Modulating Aβ Peptide Aggregation”, Nano Lett., 2009, 9, 4066-4072.

10. Min Li, Ke Deng, Sheng-Bin Lei, Yan-Lian Yang, Tai-Shan Wang, Yong-Tao Shen, Chun-Ru Wang, Qing-Dao Zeng*, Chen Wang*, “Site-Selective Fabrication of Two-Dimensional Fullerene Arrays by Using a Supramolecular Template at the Liquid-Solid Interface”, Angew. Chem. Int. Ed., 2008, 47, 6717-6721.

11. Sheng-Bin Lei, Ke Deng, Yan-Lian Yang, Qing-Dao Zeng, Chen Wang*, Jian-Zhuang Jiang*, “Electric Driven Molecular Switching of Asymmetric Tris(phthalocyaninato) Lutetium Triple-Decker Complex at the Liquid/Solid Interface”, Nano Lett., 2008, 8, 1836-1843.

12. Yanlian Yang, Qilin Chan, Xiaojing Ma, Yongtao Shen, Ke Deng, Xizeng Feng*, Chen Wang*, “Electrical conformational bistability of dimesogen molecules with a molecular chord structure”, Angew. Chem. Int. Ed., 2006, 45, 6889-6893.

Representative Books

1. Single Molecule Chemistry and Physics: An Introduction, C. Wang, C. Bai, Springer, Berlin, 2006.

2. Progress in Applications of Scanning Probe Microscopy, F.C. Zhu, C. Wang, Chemical Industry Press, 2007.

3. Innovative Method for Nanoscience and Nanotechnology, C. Wang, Y.L. Yang ed., Science Press, 2012.

Community service:

Adjunct Professor of Peking University, Jilin University, Central China Normal University and Beijing Institute of Clothing Technology, Vice President of Chinese Society of Nanoscience and Technology, Member of Chinese Vacuum Society, Executive Member of Chinese Biophysical Society, Deputy Director of Surface and Interface Physics Committee, Chinese Society of Physics, Associate Editor of Journal of Nanoparticle Research.

Commitment to research the situation:

1. The Basic Research on Standard of Nanometer Measurement Technology (National National Basic Research Program of China, MOST), Chief Scientist

2. Molecular Level Studies on Peptide Assembly Structure and Its Regulation Associated with Diseases (Major Program of NSFC), Principal Investigator

3. Basic Research on Diagnosis and Treatment Nanotechnology for Significant Chronic Diseases (Key Project of CAS), Principal Investigator

4. Self-assembled Functional Molecular Nanostructures (Sino-Danish Joint Project of NSFC), Principal Investigator