Address:

National Center for Nanoscience and Technology, China

Zhongguancun, Beiyitiao No.11,

Beijing, 100190, China

E-mail: fangqj@nanoctr.cn

Telephone: 86-10-82545562

Education:

Ph. D. 2005 Department of Biological Chemistry, Johns Hopkins University, Baltimore, MD, USA

M.S. 1999 Biochemistry Department, Peking University, Beijing, P. R. China

B.S. 1996 Department of Plant Physiology and Molecular Biology, Peking University, Beijing, P. R. China

Awards

2000 Braucher scholar Penn State University

1998 Guanghua scholar Peking University

1996 Excellent Undergraduate Student Award Peking University

1995 Pratthana Life Sciences Scholar Peking University

Research Experience

2/2013 to current Principle Investigator, National Center for Nanoscience and Technology, Beijing, China

7/2009 to 1/2013 Staff scientist, Fred Hutchinson Cancer Research Center, Seattle, WA

2/2007 to 6/2009 Post-doctoral fellow, Fred Hutchinson Cancer Research Center, Seattle, WA

10/2005 to 1/2007 Post-doctoral fellow, Department of Biological Chemistry at the Johns Hopkins University School of Medicine, Baltimore, MD

Research Interests

1. Proteomics based study of biological effects of nanomaterials and nanosafety;

2. Computational design of peptides against tumors.

Publications

1. Weizhi Wang, Menglin Li, Zewen Wei, Zihua Wang, Xiangli Bu, Wenjia Lai, Shu Yang, He Gong, Hui Zheng, Yuqiao Wang, Ying Liu, Qin Li, Qiaojun Fang*, Zhiyuan Hu*, “Bimodal Imprint Chips for Peptide Screening: Integration of High-Throughput Sequencing by MS and Affinity Analyses by Surface Plasmon Resonance Imaging”, Anal. Chem., 2014, 86 (8), 3703–3707.

2. Weizhi Wang, Zewen Wei,Di Zhang,Huailei Ma, Zihua Wang,Xiangli Bu, Menglin Li,Lingling Geng,Christopher Lausted,Leroy Hood, Qiaojun Fang, Hao Wang,* and Zhiyuan Hu*,“Rapid Screening of Peptide Probes through In Situ Single-Bead Sequencing Microarray” , Anal Chem. , 2014 Dec 2;86(23):11854-9.

3. Drescher CW, Green A, Fang QJ, Schummer M, O’Briant K, Bergan L, Martin DB, Knudsen B, Urban N, McIntosh MW. N-glycoprotein cell surface capture proteomics identifies FOLR-1 as a promising target for molecular imaging of ovarian cancer. Clinical Cancer Research (submitted)

4.Kani K, Faca VM, Hughes L, Zhang W, Fang QJ, Shahbaba B, Katz JE, Luethy R, Erde J, Schmidt J, Pitteri SJ, Zhang Q, Gross M, Tibshirani R, Plevrits SK, McIntosh MW. Jain A, Hanash S, Agus DB, Mallick P. Quantitative Proteomic profiling identifies protein correlates to EGFR kinase inhibition. Mol Cancer Ther. 2012 May;11(5):1071-81

5. Fang QJ, Kani K, Faca VM, Zhang WX, Zhang Q, Jain A, Hanash S, Agus DB, McIntosh MW and Mallick P. Impact of protein stability, cellular localization and abundance on proteomic detection of tumor-derived proteins in plasma. PLoS One 6(7):e23090. Epub 2011 Jul 29.

6. May DH, Law W , Fitzgibbon MP, Fang QJ and McIntosh MW (2009). Software Platform for Rapidly Creating Computational Tools for Mass Spectrometry-Based Proteomics. J. Proteome Res., Vol 8 (6), pp 3212–3217.

7.Fang QJ, Strand A, Law W, Faca VM, Fitzgibbon MP, Hamel N, Houle B, Liu X, May DH, Poschmann G, Roy L, Stuhler K, Ying W, Zhang J, Zheng Z, Bergeron JJ, Hanash S, He F, Leavitt BR, Meyer HE, Qian X, McIntosh MW (2009). Brain-specific proteins decline in the cerebrospinal fluid of humans with Huntington's Disease. Molecular and Cellular Proteomics Vol 8(3):451-66.

8. Fang QJ and Shortle D (2006) Protein refolding in silico with atom-based statistical potentials and conformational search using a simple genetic algorithm. Journal of Molecular Biology Vol 359:1456-1467.

9.Fang QJ and Shortle D (2005) Enhanced sampling near the native conformation using statistical potentials for local side-chain and backbone interactions Proteins: Structure, Function, and Genetics Vol60: 97-102.

10.Fang QJ and Shortle D (2005) A consistent set of statistical potentials for quantifying local side-chain and backbone interactions Proteins: Structure, Function, and Genetics Vol 60:90-96.

11.Fang QJ and Shortle D (2003) Prediction of protein structure by emphasizing local-sidechain/backbone interactions in ensembles of turn fragments Proteins: Structure, Function, and Genetics Vol 53: 486-490.

12.Selleck W, Howley R, Fang QJ, Podolny V, Fried MG, Buratowski S and Tan S (2001) A histone fold TAF octamer within the yeast TFIID transcriptional coactivator Nature Structure Biology Vol 8 (8): 695-700.