This course will focus on the basics and the applications of physical chemistry of surfaces, which are very important contents in multi-disciplines, including colloid and interface chemistry, catalysis, surface science, nanoscience and nanotechnology, etc. The first two-thirds of the course would typically stress on the fundamentals, solid-liquid interface, electrical aspects of surface chemistry, long range forces, surfaces of solids and various spectroscopic and structural methods for surface study. The important fundamentals in adsorption at the interface, nucleation and growth, wetting, LB film and self-assembly, which are crucial topics in nanoscience and nanotechnology will be discussed by combining the basics and the advances in the present research. This course will help the graduate students to improve their capability in applying basic knowledge of surface physical chemistry in advanced research.